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In my practice, it is rarely obvious

While modeled cigarette butt density was significantly higher in the top quintiles of SER, the relationship to population density explains the orders of magnitude range of cigarette butt density among census tracts within a quintile (Fig 2)

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Frequency of Use The frequency of marijuana use is the biggest determining factor

Lastly, we used SMultiXcan 21 , which examines DNA to RNA relationships ( cis- eQTLs) in specific tissues from GWAS summary statistics by training an elastic neural net algorithm on human donors from the Genotype-Tissue Expression database (GTEx) 22